Metabolic - Marek Doyle

adrenal

Semaglutide: Mechanism, Questions and Future Discussion Points

TRANSCRIPT: It started its life as a diabetes medication. More recently, it's been referred to as a celebrity weight loss drug. And since NICE - the National Institute of Clinical Excellence - have approved it for NHS prescription, it's also been the subject of several

heart rate variability

Heart Variability and Stress Explained: How to Measure It, Healthy Ranges, How to Increase It

Heart Rate Variability became an area of interest during the 70s, when it was deployed to monitor the health of newborn babies as well as to track recovery rates of athletes. Since this time, it has been shown to provide insights on the overall health

Why can’t I meditate? Discussion of the neurobiological obstacles faced by those with ME/CFS (and other inflammatory / energetic / stress disorders)

Western medicine may be late to the party but, in recent years, as begun to cultivate a relationship with meditation. And the early signs are decidedly positive; as more and more randomized controlled trials are performed, researchers are finding that meditation reduces inflammation, reduces anxiety,

cellular hypothyroidism

Low thyroid symptoms with normal lab results: what four decades of science says about the value of testing TSH and T4, recognizing cellular hypothyroidism and treatment options

Undertake any search of ‘consequences of hypothyroidism’ and you will reliably receive a laundry list of the usual symptoms; fatigue, brain fog, low mood, constipation, sensitivity to the cold, reduced hair growth and general malaise. However, the impact of hypothyroidism in the human body cannot

Is cortisol good or bad? Implications for adrenal support in ME/CFS, stress-related and inflammatory conditions

Cortisol is associated with neurotoxicity and subsequent depression, with papers showing that sustained high cortisol is associated with reduced neuroplasticity. Studies that supply animals with Prednisolone, a synthetic cortisol analog and therefore a member of the glucocorticoid family, reliably show depressive behaviours (see Gonzalez-Perez et

c8 oil

Ketogenic Diet FAQs

Ketosis is an alternative means of fueling the body and one where ketones act as the primary fuel for the central nervous system (your brain). The switch to this alternative fueling state occurs when carbohydrate availability drops and fats remain plentiful; this is important because

brain fog

Research Says that High-Fat Meals Cause Endotoxemia and Brain Fog… Except It Didn’t

From treating non-responsive epilepsy or through maintaining performance at high altitude, the benefits of ketogenic diets have been known for many decades. However, it is in the last few years that interest in this approach has skyrocketed and has induced the usual responses in the

adrenal

Zinc is Great, Unless it’s Not: Benefits, Side Effects and Personalization

Interest in zinc has progressively built since the 90s, where it’s role in supporting immunity and enhancing hormonal status began to be recognized. Focus has increased gradually in this time to reach a fever pitch during the COVID-19 chaos, as worried individuals look for proven

brain

MCAS and Sleep: How Mast Cells Mediators can Drive Insomnia

Mast Cell Activation Syndrome is the label given to individuals who experience unexplained inflammatory events that are mediated by mast cells and affect several body systems at once. Accordingly, it is often summarized as constant allergy-type symptoms in the absence of an allergen. Histamine is

Saliva Testing: Is it as Reliable as Blood Tests?

Nutritional therapy has come a long way since the era of Abram Hoffer and Linus Pauling, counter-revolutionaries whose work countered establishment paradigms and stimulated change in across a large host of medical disciplines. Arguably, the driving force in developments has been the wider range of